What is gene conversion?

Gene conversion is a process that occurs during genetic recombination in which one DNA sequence is changed to be more similar to another. This can happen through the double-strand break repair pathway, where the DNA from one chromosome is used as a template to repair the broken DNA on another chromosome, leading to the conversion of the DNA sequence.

Gene conversion can result in the transfer of genetic information between homologous chromosomes and can lead to the creation of new genetic variations. It is a common mechanism in the evolution of genomes and can contribute to genetic diversity within a population.

Gene conversion can also play a role in the development of genetic diseases, as it can cause mutations or changes in important genes. Studying gene conversion can help researchers better understand the mechanisms of genetic recombination and how it impacts the genetic makeup of organisms.